A new computational model simulating fruit fly wing development has enabled researchers to identify previously hidden mechanisms behind organ generation.

8 May 2024

Rice University Develops AI-Powered Tools for Unraveling Microbial Genomes

Since the first microbial genome was sequenced in 1995, scientists have reconstructed the genomic makeup of hundreds of thousands of microorganisms and have even devised methods to take a census of bacterial communities on the skin, in the gut, or in soil, water and elsewhere based on bulk samples, leading to the emergence of a relatively new field of study known as metagenomics.

8 May 2024

mRNA Dynamics Guide Cell Identity Formation

New research from Hebrew University sheds light on the regulation of mRNA during the development of the embryo. The research separates newly-transcribed from pre-existing mRNA in zebrafish embryos using a combination of single-cell RNA-Seq and metabolic labeling.

8 May 2024

New Insights Into PARP1 Biology Could Open Avenues to Improve Cancer Treatments

A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can lead to telomere shortening and genomic instability that can cause cancer.

8 May 2024

Herpesvirus Infection Reshapes Mitochondrial Architecture and Disrupts Metabolic Processes

Herpesvirus infection alters the host cell's mitochondria's normal structure and function, according to researchers from the University of Jyväskylä.

8 May 2024

Harnessing Gut Microbiome Compounds to Reduce Inflammation

Researchers at the University of Toronto have found naturally occurring compounds in the gut that can be harnessed to reduce inflammation and other symptoms of digestive issues.

6 May 2024

Unlocking Glucose-Driven Mechanisms of Immunosuppression in Glioblastoma

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma -; a serious and often fatal brain cancer -; suppresses the immune system so that the tumor can grow unimpeded by the body's defenses.

6 May 2024

Targeting RNA Modifications: A Novel Approach for Neuroblastoma Treatment

Neuroblastoma is a common pediatric cancer that originates in developing nerve cells outside the brain.

6 May 2024

New Insights into E. coli's UTI Survival Strategy

Due to anatomical peculiarities, women are particularly vulnerable to UTIs; nearly 50% of them will experience one at some point in their lives.

6 May 2024

Protein Complex Movement May Regulate Cell Division, Impacting Disease Research

Scientists at Umeå University in Sweden have found that the movement of a unique protein complex known as the Mediator along DNA genes may affect the process of cell division.

6 May 2024

Study Demonstrates How the Warburg Effect is Crucially Linked to Cancer Progression

Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming.

3 May 2024

Epigenomic Analysis Reveals Potential Treatment Avenues for ALS

For most patients, it's unknown exactly what causes amyotrophic lateral sclerosis (ALS), a disease characterized by degeneration of motor neurons that impairs muscle control and eventually leads to death.

3 May 2024

New Study Sheds Light on Genetic Adaptations of Papua New Guinean Populations

Papua New Guinea (PNG) has a wide range of environments, each presenting unique challenges to human survival. Highlanders and lowlanders of PNG are striking examples of populations facing distinct environmental stress.

2 May 2024

Understanding How Genetic Drivers Influence the Evolution of Photosynthesis Mechanism in Tillandsia

Researchers at the University of Vienna, along with collaborators from France, Germany, Switzerland and the USA, have achieved a major breakthrough in understanding how genetic drivers influence the evolution of a specific photosynthesis mechanism in Tillandsia (air plants).

2 May 2024